PRECISION COSMETICS FOR SKIN LONGEVITY

The keyword today is longevity: it no longer means only increasing lifespan, but extending the period lived in good health, the so-called healthspan. This also applies to the skin: not just counteracting the signs of time, but keeping it vital, youthful and healthy for longer.

Science has shown that aging is influenced only in part by genetics: about 30% is determined by our DNA, while around 70% depends on epigenetic factors such as environment, nutrition, physical activity, stress management and empathy towards the outside world.

From this awareness comes Vagheggi 75.25, the professional cosmetic line that inaugurates a new era of skin longevity. With a scientific approach grounded in studies on epigenetics and cellular longevity, this precision skincare line has been designed with active ingredients able to act on the 12 hallmarks of skin aging. 75.25 does not simply reduce the visible signs of time, but improves the vitality of the skin, thanks to actives with a rejuvenating effect equivalent to up to 8.2 years younger in biological skin age.

At the core of this revolutionary line are high-performance active ingredients such as the NAD+ Activator, which acts on the 12 hallmarks of aging, the extract of Lapacho bark, which protects telomeres while stimulating collagen, elastin and hyaluronic acid, Lavandula Hybrida, which resynchronizes the skin’s circadian rhythm, and a bio-fermentation peptide that reduces eyelid ptosis, wrinkles, puffiness and dark circles.

75.25 also introduces an absolute innovation in the world of precision cosmetics: the Efficacy Booster Device, a unique beauty tool designed to work in perfect synergy with the 75.25 Longevity Day Cream. This device combines four technologies—630 nm red light, microcurrents, heat and vibration—for targeted skin rejuvenation. An exclusive instrument that enhances the effectiveness of professional treatments within home skincare: when used alongside treatment protocols, it amplifies the results, making them faster and more visible.

75.25 is the ideal line for estheticians and beauty professionals who want to propose a new paradigm of facial treatment inspired by the science of skin longevity, capable of uniting visible results, technology and cutting-edge research.

NAD+ Activator: a cosmetic active that stimulates regenerative and repair processes by boosting energy production in the mitochondria. It helps prevent inflammaging and skin aging. Derived from sustainably cultivated sprouts, it increases the NAMPT enzyme, essential for NAD+ recycling, and promotes collagen production. Delivers a lifting and remodeling effect, with visible reduction of wrinkles and deep folds.

Lapacho Extract: protects telomeres, slowing down cellular aging and strengthening the dermo-epidermal junction. Stimulates the production of hyaluronic acid, collagen and elastin. Grown and extracted through sustainable methods.

Lavandula Hybrida Extract: mimics the action of melatonin and regulates the sleep–wake cycle of skin cells, promoting cellular regeneration and reducing signs of fatigue for a relaxed and radiant appearance. Resynchronizes the skin’s circadian rhythm and strengthens its immune defenses during the night.

Bio-fermentation Peptide: counteracts inflammaging, melanogenesis and oxidation, delivering a visible lifting effect in 28 days. Reduces eyelid ptosis, wrinkles, puffiness and dark circles. Provides targeted efficacy on the main signs of aging in the eye contour area.

EVALUATION OF THE EFFECTIVENESS OF A COSMETIC TREATMENT ON SKIN ROUGHNESS AND SMOOTHNESS
(7525 Efficacy Booster Device + Longevity Day Cream for 14 days)

Instrumental test – the instrumental assessments highlighted:
Reduction in skin roughness: –11.6%, with a maximum value of –25.4% (improved smoothness)
Average wrinkle depth: –14.8%, with a maximum value of –40%

Self-assessment test – 100% of subjects reported that the treatment improves skin firmness, radiance, hydration, and provides a lifting and remodeling effect. They also confirmed that the treatment is easy to use and sensorially pleasant.

EVALUATION OF THE EFFECTIVENESS OF THE LONGEVITY COSMETIC FACIAL TREATMENT COMBINED WITH HOME CARE AND DEVICE
(5 professional sessions, 28 days of home care and device use)

Instrumental test
Wrinkle depth: at T28 (days) –24.6%, with a maximum value of –50.8%
Eyelid sagging: at T28 (days) –26.2%, with a maximum value of –48.8%

PROFESSIONAL PRODUCTS

LONGEVITY CREAM TO OIL CLEANSER 
500 ml Bottle

LONGEVITY PRE-SERUM TONER 
500 ml Bottle

LONGEVITY PROFESSIONAL KIT 
5 treatments
- N.5 Longevity day cream 0,1 fl. oz
- N.5 Longevity eye contour 0,03 fl. oz
- N.5 Longevity Mask Net Wt.1,058 oz.
- N.1 Face concentrate 0,68 fl. oz
- N.1 Deep face massage 0,68 fl. oz
- N.1 Misuring cap

HOME CARE PRODUCTS

LONGEVITY DOUBLE CLEANSER 
150 ml Jar

LONGEVITY PRE-SERUM TONER
125 ml Bottle

LONGEVITY MELT-IN SCRUB 
80 ml Jar

LONGEVITY DAY CREAM 50ML + EFFICACY BOOSTER DEVICE 
50 ml Jar
REFILL 50 ml

LONGEVITY NIGHT CREAM 
50 ml Jar 
REFILL 50 ml

3D LONGEVITY OIL 
30 ml Bottle

LONGEVITY INTENSIVE TREATMENT KIT 
1,5 ml x 10 Vials

LONGEVITY EYE CONTOUR 
15 ml Tube

LONGEVITY FACE PERFECTOR 
15 ml Tube