Precision Skincare for Skin Longevity

Today’s key word is longevity: the focus is no longer simply on increasing lifespan, but on extending the period of life lived in good health — the so-called healthspan.

The same applies to the skin: the goal is not only to counteract the signs of aging, but to preserve its vitality, youthfulness, and health for longer.

Science has shown that aging is influenced only in part by genetics: around 70% depends on epigenetic factors such as environment, nutrition, physical activity, stress management, and our relationship with the world around us.

From this awareness comes Vagheggi 75.25: the professional cosmetic line that ushers in a new era of skin longevity.

Thanks to a scientific approach based on epigenetic and cellular longevity studies, this precision skincare line is formulated with active ingredients designed to target the 12 hallmarks of skin aging. 75.25 does not simply reduce the visible signs of time; it enhances skin vitality through actives proven in testing to rejuvenate the skin’s biological age by up to 8.2 years.

At the heart of this revolutionary line are highly performing active ingredients, including the NAD+ Activator, which acts on all 12 hallmarks of aging; Lapacho Bark Extract, which protects telomeres while stimulating collagen, elastin, and hyaluronic acid production; Lavandula Hybrida, which helps resynchronize the skin’s circadian rhythm; and a Bio-Fermentation Peptide, which reduces eyelid ptosis, wrinkles, puffiness, and dark circles.

75.25 also introduces an absolute innovation in the world of precision cosmetics: the Efficacy Booster Device, a unique beauty device specifically designed to work in perfect synergy with the 75.25 Longevity Day Cream. It combines the benefits of four technologies — 630 nm red light therapy, microcurrents, heat, and vibration — to deliver targeted skin rejuvenation.

An exclusive device that enhances the effectiveness of professional treatments within the home skincare routine: when used in synergy with the protocols, it amplifies results, making them faster and more visible.

75.25 is the ideal line for beauticians and skincare professionals seeking to offer a new facial treatment paradigm inspired by the science of skin longevity — combining visible results, advanced technology, and cutting-edge research.

NAD+ Activator: a cosmetic active that stimulates regenerative and repair processes by boosting energy production in the mitochondria. It helps prevent inflammaging and skin aging. Derived from sustainably cultivated sprouts, it increases the NAMPT enzyme, essential for NAD+ recycling, and promotes collagen production. Delivers a lifting and remodeling effect, with visible reduction of wrinkles and deep folds.

Lapacho Extract: protects telomeres, slowing down cellular aging and strengthening the dermo-epidermal junction. Stimulates the production of hyaluronic acid, collagen and elastin. Grown and extracted through sustainable methods.

Lavandula Hybrida Extract: mimics the action of melatonin and regulates the sleep–wake cycle of skin cells, promoting cellular regeneration and reducing signs of fatigue for a relaxed and radiant appearance. Resynchronizes the skin’s circadian rhythm and strengthens its immune defenses during the night.

Bio-fermentation Peptide: counteracts inflammaging, melanogenesis and oxidation, delivering a visible lifting effect in 28 days. Reduces eyelid ptosis, wrinkles, puffiness and dark circles. Provides targeted efficacy on the main signs of aging in the eye contour area.

EVALUATION OF THE EFFECTIVENESS OF A COSMETIC TREATMENT ON SKIN ROUGHNESS AND SMOOTHNESS
(7525 Efficacy Booster Device + Longevity Day Cream for 14 days)

Instrumental test – the instrumental assessments highlighted:
Reduction in skin roughness: –11.6%, with a maximum value of –25.4% (improved smoothness)
Average wrinkle depth: –14.8%, with a maximum value of –40%

Self-assessment test – 100% of subjects reported that the treatment improves skin firmness, radiance, hydration, and provides a lifting and remodeling effect. They also confirmed that the treatment is easy to use and sensorially pleasant.

EVALUATION OF THE EFFECTIVENESS OF THE LONGEVITY COSMETIC FACIAL TREATMENT COMBINED WITH HOME CARE AND DEVICE
(5 professional sessions, 28 days of home care and device use)

Instrumental test
Wrinkle depth: at T28 (days) –24.6%, with a maximum value of –50.8%
Eyelid sagging: at T28 (days) –26.2%, with a maximum value of –48.8%

PROFESSIONAL PRODUCTS

LONGEVITY CREAM TO OIL CLEANSER 
500 ml Bottle

LONGEVITY PRE-SERUM TONER 
500 ml Bottle

LONGEVITY PROFESSIONAL KIT 
5 treatments
- N.5 Longevity day cream 0,1 fl. oz
- N.5 Longevity eye contour 0,03 fl. oz
- N.5 Longevity Mask Net Wt.1,058 oz.
- N.1 Face concentrate 0,68 fl. oz
- N.1 Deep face massage 0,68 fl. oz
- N.1 Misuring cap

HOME CARE PRODUCTS

LONGEVITY DOUBLE CLEANSER 
150 ml Jar

LONGEVITY PRE-SERUM TONER
125 ml Bottle

LONGEVITY MELT-IN SCRUB 
80 ml Jar

LONGEVITY DAY CREAM 50ML + EFFICACY BOOSTER DEVICE 
50 ml Jar
REFILL 50 ml

LONGEVITY NIGHT CREAM 
50 ml Jar 
REFILL 50 ml

3D LONGEVITY OIL 
30 ml Bottle

LONGEVITY INTENSIVE TREATMENT KIT 
1,5 ml x 10 Vials

LONGEVITY EYE CONTOUR 
15 ml Tube

LONGEVITY FACE PERFECTOR 
15 ml Tube

75.25 LUMISCULPT FACE MASK
KIT 3 masks